68363-44-0Relevant articles and documents
Synthesis and antibacterial evaluation against resistant Gram-negative bacteria of monobactams bearing various substituents on oxime residue
Li, Zhi-Wen,Lu, Xi,Wang, Yan-Xiang,Hu, Xin-Xin,Fu, Hai-Gen,Gao, Li-Mei,You, Xue-Fu,Tang, Sheng,Song, Dan-Qing
, (2019/12/25)
Based on the structural characteristics of aztreonam (AZN) and its target PBP3, a series of new monobactam derivatives bearing various substituents on oxime residue were prepared and evaluated for their antibacterial activities against susceptible and res
DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS
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, (2017/11/10)
Provided herein are deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams, pharmaceutical compositions thereof and methods of treating infectious disease with deuterated compounds or pharmaceutical compositions thereof.
OXAMAZIN ANTIBIOTICS
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Paragraph 00169; 00170, (2014/10/18)
Disclosed herein are oxamazin monobactam compounds and their use as antibiotics resistant to degradation by β-lactamases. Also disclosed are pharmaceutical compositions containing the compounds and methods of synthesis.