114884-40-1

Upstream product

• 67987-67-1 (4S)-4-(2-iodoethyl)-2,2-dimethyl-1,3-dioxolane 
• 603-35-0 triphenylphosphine 
• 5754-34-7 2-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-ethanol 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 
• 95422-24-5 methyl (3S)-3,4-O-isopropylidene-3,4-dihydroxybutanoate 
• 94992-56-0 (S)-1,2-O-isopropylidene-4-O-<(4-methylphenyl)sulfonyl>-1,2,4-butanetriol 

Downstream Products

• 935553-92-7 (S)-(Z)-1-[1'-(triphenylmethyl)-1'H-imidazol-4'-yl]-4,5-O-isopropylidene-pent-1-en-4,5-diol 
• 160765-92-4 (4Z)-9-benzoyl-3,4,5-trideoxy-1,2:7,8-di-O-isopropylidene-D-manno-non-4-enitol 
• 160765-93-5 4,5-anhydro-9-benzoyl-3-deoxy-1,2:7,8-di-O-isopropylidene-D-erythro-D-galactononitol 
• 160765-95-7 (4R,5R)-5-<(1R,2R)-3-benzoyloxy-1,2-(isopropylidenedioxy)propyl>-4,5-dihydro-4-<(1S,3S)-1-hydroxy-3,4-(isopropylidenedioxy)butyl>-2-trichloromethyl-1,3-oxazole 
• 160765-96-8 9-benzoyl-3,5-dideoxy-1,2:7,8-di-O-isopropylidene-5-trichloroacetamido-D-erythro-L-glucononitol 
• 114828-16-9 Benzyl-[(E)-(S)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-but-2-enyl]-carbamic acid benzyl ester 
• 114828-14-7 Benzyl-[(Z)-(S)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-but-2-enyl]-carbamic acid benzyl ester 
• 114884-42-3 (4S,5S)-3-Benzyl-5-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-4-methyl-oxazolidin-2-one 
• 114828-15-8 (4S,5R)-3-Benzyl-5-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-4-methyl-oxazolidin-2-one 
• 114884-41-2 (4S,5R)-3-Benzyl-5-[(S)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-4-methyl-oxazolidin-2-one 
• 114828-17-0 (4S,5S)-3-Benzyl-5-[2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-4-methyl-oxazolidin-2-one 
• 211518-43-3 N-{(1R,2S)-4-(tert-Butyl-diphenyl-silanyloxy)-1-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-phenylselanyl-ethyl]-2-hydroxy-butyl}-2,2,2-trichloro-acetamide 
• 211570-35-3 N-{(1S,2S)-4-(tert-Butyl-diphenyl-silanyloxy)-1-[(E)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-vinyl]-2-hydroxy-butyl}-2,2,2-trichloro-acetamide 
• 211570-33-1 (Z)-(S)-1-(tert-Butyl-diphenyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hex-4-en-3-ol 

Relevant academic research and scientific papers

SYNTHESIS OF RESOLVINS AND INTERMEDIATES, COMPOUNDS PREPARED THEREBY, AND USES THEREOF

Methods are disclosed for the preparation of a new class of lipid mediators known as resolvins, with Resolvin D6 (4,17-dihydroxy-5E,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid) being exemplary. Also disclosed are methods for the efficient synthesis of key int

Stereocontrolled synthesis of enantiomeric imidazolopiperidinoses and imidazoloazepanoses using Wittig/dihydroxylation reactions

A new route for the synthesis of imidazolosugars-6-deoxyimidazolopiperidinoses 1 and 2 and 7-deoxyimidazoloazepanoses 3?and 4 in two enantiomerical forms-is reported. The new synthetic approach is based on two key reactions: (i) stereocontrolled Wittig Z-

Imidazo[1,2-a]pyridine C-nucleosides as antiviral agents

This invention pertains to nucleoside analogs that have antiviral activity and improved metabolic stability, compositions comprising them, and methods of antiviral treatment employing them. More particularly, this invention pertains to imidazo[1,2-a]pyridine C-nucleosides, as exemplified by compounds such as imidazo[l,2-a]pyridine C5-nucleosides and imidazo[1,2-a]pyridine C3-nucleosides, and may be represented by formula (I), wherein exactly one of Q3and Q5is a sugar-like moiety; exactly one of Q3and Q5is —H; and Q2, Q6, Q7and Q8are independently imidazo[1,2-a]pyridine substituents, such as —H, —F, —Cl, —Br and —I.

A new practical enantiospecific synthesis of unlabelled and tritium labelled 12-HETEs

The oxidative metabolism of arachidonic acid AA is known to yield a variety of biologically active substances.Among them, both enantiomers of 12-hydroxyeicosatetraenoic acid (12-HETE) have been the subject of much interest.In order to extend their biologi

STEREOCONTROLLED SYNTHESIS OF 6-epi-D-PURPUROSAMINE B BY IODOCYCLOCARBAMATION OF A CHIRAL Z-OLEFIN DERIVED FROM L-ALANINE AND L-MALIC ACID

6-epi-D-Purpurosamine B was synthesized efficiently through a chiral Z-olefin 8 derived from L-alanine and L-malic acid under complete stereochemical control by using iodocyclocarbamation as the key reaction.