114953-71-8

Usage

Uses

Used in Pharmaceutical Industry:
((S)-1-Chloro-2,2,2-trifluoro-ethylsulfanyl)-benzene is used as an intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and properties.
Used in Agrochemical Industry:
((S)-1-Chloro-2,2,2-trifluoro-ethylsulfanyl)-benzene is used as an intermediate in the production of agrochemicals, contributing to the development of effective and efficient crop protection products.
Used in Organic Synthesis:
((S)-1-Chloro-2,2,2-trifluoro-ethylsulfanyl)-benzene is used as a solvent, reagent, and intermediate in organic synthesis, enabling the creation of a wide range of organic compounds.
Used in Polymer Production:
((S)-1-Chloro-2,2,2-trifluoro-ethylsulfanyl)-benzene is used in the production of polymers and other materials, providing unique properties and enhancing the performance of the final products.
It is important to handle and use ((S)-1-Chloro-2,2,2-trifluoro-ethylsulfanyl)-benzene with proper safety precautions, as exposure to high concentrations can be harmful to human health.

Upstream product

• 2262-07-9 2,2,2-trifluoroethyl phenyl sulfide 
• 151-67-7 1,1,1-trifluoro-2-bromo-2-chloroethane 
• 108-98-5 thiophenol 

Downstream Products

• 123228-01-3 1-{2,2,2-trifluoro-1-(phenylsulfanyl)ethyl}naphthalene 
• 129286-70-0 N-<2,2,2-trifluoro-1-(phenylthio)ethyl>-2-phenylethanamide 
• 61698-70-2 2,2-difluorovinyl phenyl sulfide 
• 156082-34-7 (1-Chloro-2,2,2-trifluoro-ethanesulfinyl)-benzene 
• 123228-04-6 2,2,2-trifluoro-1-(4-methoxyphenyl)ethyl phenyl sulfide 
• 123228-03-5 2,2,2-trifluoro-1-(2-methoxyphenyl)ethyl phenyl sulfide 
• 129286-69-7 N-<2,2,2-trifluoro-1-(phenylthio)ethyl>benzamide 
• 123247-37-0 2,2,2-trifluoro-1-<2-(N,N-dimethylamino)phenyl>ethyl phenyl sulfide 
• 129286-51-7 2,2,2-trifluoro-1-(2-phenethylphenyl)ethyl phenyl sulfide 
• 129286-52-8 2,2,2-trifluoro-1-(4-phenethylphenyl)ethyl phenyl sulfide 
• 129286-71-1 N-<2,2,2-trifluoro-1-(phenylthio)ethyl>-3-butenamide 
• 129286-49-3 2,2,2-trifluoro-1-(4-methylphenyl)ethyl phenyl sulfide 
• 129286-48-2 2,2,2-trifluoro-1-(2-methylphenyl)ethyl phenyl sulfide 
• 129286-68-6 N-<2,2,2-trifluoro-1-(phenylthio)ethyl>acetamide 

Relevant academic research and scientific papers

A facile synthesis of 1-chloro-2,2,2-trifluoroethyl sulfides

A facile synthesis of structurally diverse 1-chloro-2,2,2-trifluoroethyl sulfides from readily available 1-bromo-1-chloro-2,2,2-trifluoroethane (Halothane) and various aliphatic and aromatic thiols in the presence of sodium dithionite/sodium bicarbonate is described. The synthetic utility of the prepared sulfides is illustrated by the synthesis of biologically potent heterocycles and by their electrophilic reactions with thiophene.

Stereochemical study of the allylation of 1-phenylsulfinylethyl and 1- phenylsulfinyl-2,2,2-trifluoroethyl radicals

The stereochemistry of the reactions of 1-phenylsulfinylethyl radical (1r) and 1-phenylsulfinyl-2,2,2-trifluoroethyl radical (2r) with allylstannanes has been examined. Preferential formation of products of opposite relative configuration has been observe

Generation and Electrophilic Reactions of the 2,2,2-Trifluoro-1-(phenylthio)ethyl Carbocation

2,2,2-Trifluoro-1-(phenylthio)ethyl carbocation (4) has been generated by the reaction of 1-chloro-2,2,2-trifluoroethyl phenyl sulfide (7b) with ZnCl2 in nitromethane or SnCl4 in 1,2-dichloroethane.The carbocation 4 can be trapped with various aromatics b

GENERATION AND REACTION OF 2,2,2-TRIFLUORO-1-PHENYLSULFENYLETHYL CARBOCATION

Lewis acid-catalyzed dechlorination of 1-chloro-2,2,2-trifluoroethyl phenyl sulfide generates 2,2,2-trifluoro-1-phenylsulfenylethyl carbocation which undergoes electrophilic reaction with aromatic compounds.

SYNTHESIS OF FLUORINATED VINYL SULFIDES AND SELENIDES

The reaction between fluoroolefins 1 and 10e and benzenesulfenyl or selenenyl halides 6 is found to be solvent-dependent and gives in most cases predominantly the regioisomer 8.The structure of adducts 8 and 9 are ascertained by 1H, 19F and 77Se NMR spectroscopy.Compounds 8 are easily halogenated and treatment of the products with magnesium or zinc leads to the desired polyfluorovinyl sulfides and selenides 10.A second route of synthesis of these reagents results from the reaction of fluorovinyllithio-derivatives 11 with benzenesulfenyl or selenenyl halides.Olefin 10e is also obtained from the selenoacetal 8t of trifluoroacetaldehyde.