114953-96-7Relevant articles and documents
Tricyclic heteroaromatic systems: Synthesis, [3H]flunitrazepam brain membrane binding inhibition, and structure-activity relationships of 2,3-dihydro-2-aryl-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones
Colotta,Cecchi,Melani,Palazzino,Filacchioni,Martini,Giannaccini,Lucacchini
, p. 239 - 242 (2007/10/02)
We report the synthesis and binding activity to the central benzodiazepine receptors of some 2,3-dihydro-2-ary-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones, which are isosteres of the CGS series. Although the compounds of the CGS series are potent ligands of