114971-41-4Relevant academic research and scientific papers
Au-Catalyzed Stereoselective Ritter Reaction of Haloalkynes with Nitriles for (Z)-β-Halogenated Enamides
Liu, Congrong,Yang, Fulai
supporting information, p. 6867 - 6870 (2019/11/11)
An efficient and stereoselective protocol has been developed for the synthesis of (Z)-β-halogenated enamide through gold catalyzed Ritter reaction. In the presence of 2 mol% BrettPhosAuCl and 2 mol% AgNTf2, a broad range of nitriles smoothly underwent Ritter reaction with aromatic, vinylic or aliphatic haloalkynes to give structurally diverse (Z)-β-halogenated enamides in excellent to good yields.
Copper-catalyzed direct synthesis of iodoenamides from ketoximes
Liang, Hao,Ren, Zhi-Hui,Wang, Yao-Yu,Guan, Zheng-Hui
, p. 9789 - 9794 (2013/08/23)
Iodide in copper's pathway: A new, efficient, and practical copper-catalyzed synthesis of Z-iodoenamides from readily available ketoximes has been developed (see scheme). The reaction was believed to proceed through a single-electron-transfer pathway. The corresponding Z-iodoenamides have been applied to the synthesis of substituted oxazoles, dienes, β-phenoxyl enamides, eneynes, β-acylenamides, and pyrroles (DCE=1,2-dichloroethane). Copyright
Preparation of Enamides via Reductive Acylation of N-Acetoxyimino Compounds by Use of Fe3(CO)12
Nakanishi, Saburo,Hirano, Takehiro,Otsuji, Yoshio,Itoh, Keiji
, p. 2167 - 2168 (2007/10/02)
Treatment of N-acetoxyimino compounds with Fe3(CO)12 in the presence of acyl halides and triethylamine gave enamides in good yields.
