114971-53-8

Basic information

• Product Name: 2,5-DIMETHYL-4-IODOPHENOL
• Synonyms: 2,5-DIMETHYL-4-IODOPHENOL;4-IODO-2,5-DIMETHYLPHENOL;2,5-Dimethyl-4-iodophenol 98%;2-Hydroxy-5-iodo-p-xylene;2,5-Dimethyl-4-iodophenol98%
• CAS NO: 114971-53-8
• Molecular Formula: C₈H₉IO
• Molecular Weight: 248.06
• Mol File: 114971-53-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 95-97
• Boiling Point: 284.9 °C at 760 mmHg
• Flash Point: 126.1 °C
• Appearance: /
• Density: 1.74 g/cm³
• Vapor Pressure: 0.00168mmHg at 25°C
• Refractive Index: 1.629
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2,5-DIMETHYL-4-IODOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYL-4-IODOPHENOL(114971-53-8)
• EPA Substance Registry System: 2,5-DIMETHYL-4-IODOPHENOL(114971-53-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 114971-53-8(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHYL-4-IODOPHENOL is a chemical compound with the molecular formula C8H9IO and a molecular weight of 270.06 g/mol. It is a phenolic compound with a dimethyl group and an iodine atom attached to the phenol ring. This chemical is used as a building block in the synthesis of various organic compounds. It is also utilized in the pharmaceutical industry for the production of medications and as a reagent in chemical reactions. 2,5-DIMETHYL-4-IODOPHENOL is known for its potential biological activities and is a subject of research for its potential medicinal and industrial applications.

InChI:InChI=1/C8H9IO/c1-5-4-8(10)6(2)3-7(5)9/h3-4,10H,1-2H3

Upstream product

• 95-87-4 2,5-Dimethylphenol 

Downstream Products

• 1042110-06-4 5-[3-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetylamino]-ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)propionylamino]isophthalic acid 
• 1042110-04-2 dimethyl 5-[3-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetyl-amino]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)propionylamino]-isophthalate 
• 1042110-63-3 4-{4-[2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetylamino]phenylethynyl}benzoic acid 
• 1042110-28-0 5-[2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetylamino]isophthalic acid 
• 1042110-59-7 2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)-N-(4-trimethylsilanylethynylphenyl)acetamide 
• 1042110-26-8 dimethyl 5-[2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetylamino]isophthalate 
• 1042110-61-1 N-(4-ethynylphenyl)-2-(2,5,2',4',6'-pentamethyl-biphenyl-4-yloxy)acetamide 
• 1042110-57-5 N-(4-iodophenyl)-2-(2,5,2',4',6'-pentamethylbiphenyl-4-yloxy)acetamide 
• 85223-94-5 4-hydroxy-2,5-dimethylbenzonitrile 
• 217660-56-5 2-(2,5-dimethyl-4-hydroxyphenyl)-6-methoxybenzo[b]thiophene 
• 920270-43-5 1-(2-butoxyethoxy)-4-iodo-2,5-dimethylbenzene 
• 27023-05-8 methyl 4-hydroxy-2,5-dimethylbenzoate 
• 922529-58-6 4-[1-(tert-butoxycarbonyl)-(2S)-pyrrolidinylmethoxy]-2,5-dimethyl-1-iodobenzene 

Relevant articles and documents

Synthesis and characterization of PPV monomer for subsequent electropolymerization

Organic synthesis of the monomer of poly(p-phenylenevinylene) was performed starting by the 2,5-dimethylphenol compound. An iodine atom was added to one end of the aromatic ring and then the iodine atom was substituted by a cyano group. Opposite to the cy

A green reagent for the iodination of phenols

A new reagent (I2/NaNO2) for the iodination of the aromatic ring of phenols has been discovered. The reaction proceeds at room temperature in 1.5-6 hours. In the presence of this reagent, iodinated compounds are regioselectively formed in significant yields from the corresponding substrates. Georg Thieme Verlag Stuttgart.

Iodination of Phenols by Use of Benzyltrimethylammonium Dichloroiodate(1-)

The reaction of phenols with benzyltrimethylammonium dichloroiodate(1-) in dichloromethane-methanol in the presence of CaCO3 or NaHCO3 for several hours at room temperature gave iodophenols in good yields.