114995-75-4

Upstream product

• 79-22-1 methyl chloroformate 
• 63888-21-1 benzyl 3-phenyl-2-propynoate 
• 52267-39-7 benzyl methyl malonate 
• 100-52-7 benzaldehyde 

Downstream Products

• 60935-26-4 tricyclo(3.1.0.0^2,4)hexane-3,6-dione bis(propane-1,3-diyl) ketal 
• 114995-78-7 trans-benzyl methyl 2-phenyl-6,10-dioxaspiro<4.5>dec-3-ene-1,1-dicarboxylate 
• 114995-79-8 cis-benzyl methyl 2-phenyl-6,10-dioxaspiro<4.5>dec-3-ene-1,1-dicarboxylate 

Relevant academic research and scientific papers

Hydrostannylation-cross-coupling strategy for the stereoselective synthesis of alkylidenemalonates and related α,β-unsaturated esters

A method for the stereoselective synthesis of alkylidenemalonates and related α,β-unsaturated esters by a hydrostannylation-cross-coupling process has been developed. Pd-catalyzed and radical hydrostannylation of propiolate derivatives stereoselectively provided α-alkoxycarbonyl (E)- and (Z)-vinylstannanes, respectively, which were then converted into alkylidenemalonates by the Stille coupling reaction. A one-pot process was also realizable for the Pd-catalyzed reactions.

Thermal Cycloaddition Reactions of ?-Delocalized Singlet Vinylcarbenes: Three-Carbon 1,1-/1,3-Dipoles. The Thermal Three-Carbon + Two-Carbon Cycloaddition

Full details of investigations defining new aspects of the scope and mechanism of the three-carbon + two-carbon cycloaddition reaction of ?-delocalized singlet vinylcarbenes (three-carbon 1,1-/1,3-dipoles generated in a reversible, thermal ring opening of cyclopropenone ketals) are detailed.