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1150-44-3

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1150-44-3 Usage

General Description

(±)-Isochanoclavine I is a natural compound belonging to the class of ergot alkaloids, known for their diverse pharmacological activities. It is derived from the fungus Penicillium, and has been reported to have significant anti-inflammatory, anti-microbial, and anti-cancer properties. The compound also exhibits potential antifungal activity, and has been studied for its ability to inhibit the growth of certain fungi. Additionally, research has shown that (±)-Isochanoclavine I may have potential therapeutic applications in the treatment of neurological disorders, as it has been found to modulate the levels of certain neurotransmitters in the brain. Overall, (±)-Isochanoclavine I is a promising compound that continues to be the subject of ongoing research and exploration for its various potential therapeutic uses.

Check Digit Verification of cas no

The CAS Registry Mumber 1150-44-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,5 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1150-44:
(6*1)+(5*1)+(4*5)+(3*0)+(2*4)+(1*4)=43
43 % 10 = 3
So 1150-44-3 is a valid CAS Registry Number.

1150-44-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Isochanoclavin-(I)

1.2 Other means of identification

Product number -
Other names (Z)-2-Methyl-3-((4R,5R)-4-methylamino-1,3,4,5-tetrahydro-benzo[cd]indol-5-yl)-prop-2-en-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1150-44-3 SDS

1150-44-3Relevant articles and documents

Biomimetic Total Syntheses of Clavine Alkaloids

Chaudhuri, Saikat,Bhunia, Subhajit,Roy, Avishek,Das, Mrinal K.,Bisai, Alakesh

, p. 288 - 291 (2018/01/17)

Biomimetic total syntheses of either enantiomers of a number of ergot alkaloids, chanoclavine I (1b), chanoclavine I aldehyde (1c), pyroclavine (1e), festuclavine (1f), pibocin A (1g), 9-deacetoxyfumigaclavine C (1h), and fumigaclavine G (1i), have been achieved from seco-agroclavine (1a). The advanced intermediate for seco-agroclavine (1a) was synthesized via a key thiourea-catalyzed intramolecular nitronate addition onto α,β-unsaturated ester.

Synthetic studies directed toward ergot alkaloids, (±)-6,7-secoagroclavine, (±)-chanoclavine-1, (±)-chanoclavine-II, and (±)-agroclavine-I, by an efficient and common synthetic route

Yamada, Fumio,Makita, Yoshihiko,Somei, Masanori

, p. 599 - 620 (2008/03/12)

Novel three synthetic routes to (±)-6,7-secoagroclavine were developed from either methyl 3-(3-formylindol-4-yl)acrylate, indole-4-carbaldehyde, or 4-iodoindole-3-carbaldehyde. The total syntheses of (±)-chanoclavine-I, (±)-chanoclavine-II, and (±)-agroclavine-I were accomplished as well from the synthetic intermediates involved in the synthesis of (±)-6,7-secoagroclavine, culminating in establishing an efficient and common synthetic method for ergot alkaloids.

Total synthesis of optically active chanoclavine-I

Yokoyama, Yuusaku,Kondo, Kazuhiro,Mitsuhashi, Masako,Murakami, Yasuoki

, p. 9309 - 9312 (2007/10/03)

The total synthesis of optically active chanoclavine-I, an ergot alkaloid, was accomplished using palladium-catalyzed intramolecular cyclization (Heck-reaction) as a key step. The conjugate ester (6) was obtained in 2 steps from optically active 4-bromotryptophan (10), and the cyclization of 6 proceeded smoothly without racemization to give the key intermediate, tricyclic tetrahydrobenz[c,d]indole derivative (7), in high yield.

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