115018-83-2Relevant academic research and scientific papers
Enantioselective hydrogenation of pyrrolidine-2,3,5-triones over the Pt- cinchonidine system
Szabo,Kuenzle,Mallat,Baiker
, p. 61 - 76 (2007/10/03)
1- and 4-Substituted pyrrolidine-2,3,5-triones 5, 6 and 9 have been synthesized and hydrogenated to 3-hydroxy derivatives 10-12 with 17-91% ee using a 5 wt% Pt/Al2O3 catalyst in the presence of small amounts of cinchonidine. The infl
α-Ketodicarboxylic Acid Chloride Imide Chlorides in the Synthesis of Heterocycles, III.- A Novel Wittig-Smiles Reaction.
Capuano, Lilly,Bettinger, Arthur,Engel, Michael,Pfordt, Martin,Huch, Volker
, p. 913 - 916 (2007/10/02)
N-Cyclohexyl-2,2-dimethyl-3-oxosuccinyl chloride imide chloride (1) reacts with methylenetriphenylphosphoranes affording 3-benzylidene-1-cyclohexyl-4,4-dimethyl-2,5-pyrrolidinediones 10 through a novel Wittig-Smiles mechanism.The structure of compound 10a
