1150313-03-3Relevant academic research and scientific papers
Synthesis of (3R,5R)-harzialactone a and its (3R,5S)-isomer
Sabitha, Gowravaram,Srinivas, Rangavajjula,Das, Sukant K.,Yadav, Jhillu S.
supporting information; experimental part, (2010/07/18)
The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.
Chemoenzymatic asymmetric synthesis of harzia lactone A stereomers
Kumar, Abha N.,Bhatt, Suchitra,Chattopadhyay, Subrata
experimental part, p. 205 - 209 (2009/06/06)
A facile chemoenzymatic synthesis of the harzia lactone A enantiomers was developed. A lipase-catalyzed acylation and an enantio-controlled substrate and reagent-controlled Sharpless' asymmetric dihydroxylation are the key features of the synthesis.
