115032-64-9

Upstream product

• 7212-39-7 (4-methoxymethoxyphenyl)methanol 
• 25458-49-5 1-(methoxymethoxy)-4-methylbenzene 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 436-05-5 (±)-curine 
• 1350883-54-3 C₃₃H₃₃NO₇ 
• 852612-20-5 1-{2,4-Bis-methoxymethoxy-6-[(E)-2-(4-methoxymethoxy-phenyl)-vinyl]-phenyl}-2-methyl-propan-1-one 
• 852612-19-2 2-Bromo-1,5-bis-methoxymethoxy-3-[(E)-2-(4-methoxymethoxy-phenyl)-vinyl]-benzene 
• 852612-17-0 2-Bromo-1,5-dimethoxy-3-[(E)-2-(4-methoxymethoxy-phenyl)-vinyl]-benzene 
• 144336-64-1 diethyl [4-(methoxymethoxy)benzyl]phosphonate 

Relevant academic research and scientific papers

A Modular Access to (±)-Tubocurine and (±)-Curine - Formal Total Synthesis of Tubocurarine

Two consecutive Cu-catalyzed Ullmann-type C-O couplings permitted the first successful entry toward the curare alkaloids (±)-tubocurine and (±)-curine. Starting from vanillin, the synthetic sequence comprises 15 linear steps and includes a total of 24 transformations. In addition, the total synthesis of tubocurine represents a formal total synthesis of the famous arrow poison alkaloid tubocurarine.

N-(3-pyridylalkyl)sulfonamide compounds which have useful pharmaceutical activity

Illustrative examples of the N-(3-pyridylalkyl)sulfonamide derivative are represented by the following formulae [II] and [III]: STR1 The derivatives are available for a thromboxane A2 production inhibitor, a thromboxane A2 antagonist, a prostaglandin H2 antagonist, an anti-thrombus agent, a thrombus-preventing agent and an anti-allergy agent.

Stereoselectivity Differences in Wittig Reactions of Semistabilized Ylides

The Wittig reactions of phosphorane 1 with various benzaldehydes 3 (series A) and the phosphoranes 4 with salicylaldehyde 6 (series B) have been studied.The Z:E stilbene ratio in series B is enhanced relative to that in series A.This difference in the ste