115051-47-3

Basic information

• Product Name: 2-hydroxy-2-phenyl-propionaldehyde-oxime
• Synonyms: 2-hydroxy-2-phenyl-propionaldehyde-oxime
• CAS NO: 115051-47-3
• Molecular Weight: 165.192
• Mol File: 115051-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-2-phenyl-propionaldehyde-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-2-phenyl-propionaldehyde-oxime(115051-47-3)
• EPA Substance Registry System: 2-hydroxy-2-phenyl-propionaldehyde-oxime(115051-47-3)

Safety Data

• Hazardous Substances Data: 115051-47-3(Hazardous Substances Data)

Upstream product

• 306-44-5 propanone 1-oxime 
• 145614-21-7 (E)-2-phenyl-2-<1-phenyl-5(1H)-tetrazolylthio>propanal oxime 

Downstream Products

• 17643-24-2 (+/-)-1-amino-2-phenylpropan-2-ol 
• 28144-67-4 2-phenylallylamine 
• 60860-35-7 2-(acetyloxy)-2-phenylpropanal 
• 109045-76-3 (2-phenylprop-1-en-3-yl)trimethylammonium iodide 
• 4361-50-6 2-hydroxy-2-phenyl-propionaldehyde 

Relevant articles and documents

Kinetics and Mechanism of the Alkaline Release of Phenyl(mercapto)tetrazoles from α-Oximes

Compounds such as α-phenyl(mercapto)tetrazole (PMT) oxime (9) undergo rapid elimination of the PMT anion in base via a nitrosoene intermediate.Solution kinetics and HPLC analysis of reaction products are consistent with the mechanism shown in Scheme 2.For open chain oximes such as 4, substitution α to the oxime increases the rate of release of PMT and is attributed to the relief of strain when a crowded reactant is converted to a less-crowded product.For cyclic oximes, the six-membered ring compounds are more reactive than the corresponding five-membered compounds.A linear isokinetic relationship between the entropy and enthalpy of activation was found with β = 346 +/- 51 K.Entropies of activation were found to range from -7 to +24 c.u. (1 c.u. = 4.184 J mol-1 K-1) and support the proposed mechanism.