60860-35-7

Upstream product

• 37973-52-7 (Z)-2-Phenylprop-1-en-1-yl acetate 
• 37973-51-6 (E)-2-Phenylprop-1-en-1-yl acetate 
• 115051-47-3 2-hydroxy-2-phenyl-propionaldehyde-oxime 
• 34713-70-7 2-Phenylpropanal 

Downstream Products

• 80248-52-8 Acetic acid 1-(4,4-dimethoxy-3-methyl-oxetan-2-yl)-1-phenyl-ethyl ester 
• 76299-64-4 5-Methyl-5-phenyl-3-phenylsulfanylmethyl-5H-furan-2-one 
• 80248-57-3 1-(4,4-Dimethoxy-3-methyl-oxetan-2-yl)-1-phenyl-ethanol 

Relevant academic research and scientific papers

α-Oxygenation of Aldehydes and Cyclic Ketones by Acylation-Rearrangement of Nitrones

The reaction of N-tert-butylnitrones (1a-e) of aldehydes and N-methylnitrones (2 and 3) of cyclic ketones with acid chlorides in the presence of triethylamine afforded α-acyloxy imines by rearrangement of N-vinyl-O-acylhydroxylamine intermediates.Hydrolysis of the α-acyloxy imines gave α-acyloxy aldehydes and ketones.The acylation-rearrangement reaction offers a new method for α-oxygenation of carbonyl compounds.

Allergenic α-Methylene-γ-lactones. General Method for the Preparation of β-Acetoxy- and β-Hydroxy-α-methylene-γ-butyrolactones from Sulfoxides. Application to the Synthesis of a Tuliposide B Derivative

A general synthesis of β-hydroxy-α-methylene-γ-butyrolactones , which is based on the sulfoxide-sulfenate rearrangement, is presented.Several β-acetoxy-α-methylene-γ-butyrolactones have been prepared and transformed into the β-hydroxy-derivatives through base hydrolysis.This synthesis has been applied to the first preparation of (tetraacetoxybenzyl)tuliposide B (22).

Chemistry of ketene acetals IV. A simple and general method for the preparation of 4-hydroxy-γ-butyrolactones and 2-butenolides from 1,1-dimethoxypropene and α-acyloxy aldehydes and ketones

α-Acyloxy aldehydes (2a,b) react with 1,1-dimethoxypropene (1) in the presence of ZnCl2 to yield 2,2-dimethoxy-3-methyloxetanes (3a,b).Stronger electron-withdraving acyl groups are necessary for the analogous conversion of α-acyloxy ketones (2c,d,e).Hydro