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Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-(pyrrolidin-1-yl)pyridine is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic applications.
Used in Chemical Industry:
3-Bromo-2-(pyrrolidin-1-yl)pyridine is used as a building block for synthesizing other organic chemicals. Its versatility in chemical reactions makes it a valuable component in the development of new chemical products.
Used in Research and Development:
3-Bromo-2-(pyrrolidin-1-yl)pyridine is employed as a research compound in academic and industrial laboratories. It serves as a starting material for exploring new chemical reactions and understanding the properties of related compounds.

Upstream product

• 123-75-1 pyrrolidine 
• 52200-48-3 3-bromo-2-chloropyridine 

Relevant academic research and scientific papers

SHP2 INHIBITORS

The present invention relates to new compounds capable of inhibiting the activity of SHP2 phosphatase, having the general Formula (I).

Co(II)-Catalyzed Regioselective Pyridine C-H Coupling with Diazoacetates

A Co(II)-catalyzed pyridyl C-H bond carbenoid insertion with α-diazoacetates has been realized. This transformation features a highly regioselective C-C bond formation at the C3-position of pyridines, providing an efficient access to diverse α-aryl-α-pyri

BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME

Provided is a compound showing excellent antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof: wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH2, C=O, NH, O, S or the like; X1, X2 and X3 are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are each a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.

PHARMACEUTICALS COMPRISING BIARYL DERIVATIVES OR SALTS THEREOF

PROBLEM TO BE SOLVED: To provide compounds with excellent antimycotic activity against Trichophyton. SOLUTION: The invention provides pharmaceuticals comprising biaryl derivatives represented by general formula (I) or salts thereof, where ring A is optionally substituted phenyl or the like; Q is CH2 or the like; X1, X2 and X3 are CR1 or the like; and Y is CH or N. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT