1150591-57-3Relevant academic research and scientific papers
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy
Capela, Rita,Cabal, Ghislain G.,Rosenthal, Philip J.,Gut, Jiri,Mota, Maria M.,Moreira, Rui,Lopes, Francisca,Prudencio, Miguel
experimental part, p. 4698 - 4706 (2012/03/26)
It is widely accepted that the struggle against malaria depends on the development of new strategies to fight infection. The "magic bullet" thought to be necessary to reach eradication should not only provide treatment for all Plasmodium spp. that infect
Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates
Araujo, Nuna C.P.,Barton, Victoria,Jones, Michael,Stocks, Paul A.,Ward, Stephen A.,Davies, Jill,Bray, Patrick G.,Shone, Alison E.,Cristiano, Maria L.S.,O'Neill, Paul M.
scheme or table, p. 2038 - 2043 (2009/11/30)
A novel series of semi-synthetic trioxaquines and synthetic trioxolaquines were prepared, in moderate to good yields. Antimalarial activity was evaluated against both the chloroquine-sensitive 3D7 and resistant K1 strain of Plasmodium falciparum and both
