115081-94-2

Usage

Uses

Used in Chemical Synthesis:
7-IODO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE is used as a reagent in chemical reactions for its ability to participate in various organic synthesis processes. Its unique structure with a benzooxazine ring and carbonyl groups makes it a valuable component in the formation of more complex organic molecules.
Used in Research and Development:
In the field of research and development, 7-IODO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE is employed as a research chemical to explore its properties and potential applications in advancing scientific knowledge and developing new materials or compounds.
Used in Pharmaceutical Industry:
7-IODO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE is used as an intermediate in the synthesis of pharmaceutical compounds for its potential role in the development of new drugs. Its unique structure may contribute to the creation of novel therapeutic agents.
Used in Material Science:
In material science, 7-IODO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE is used as a component in the development of new materials, potentially influencing their properties and performance due to its structural characteristics.

Upstream product

• 20780-77-2 6-iodoisatin 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 20776-54-9 2-amino-4-iodobenzoic acid 

Downstream Products

• 1241915-20-7 2-amino-4-iodobenzamide 
• 144550-76-5 methyl 2-amino-4-iodobenzoate 

Relevant academic research and scientific papers

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Synthesis and nematicidal activities of 1,2,3-benzotriazin-4-one containing 4,5-dihydrothiazole-2-thiol derivatives against Meloidogyne incognita

A series of novel 1,2,3-benzotriazin-4-one derivatives containing 4,5-dihydrothiazole-2-thiol were synthesized and characterized by 1H NMR, 13C NMR, 19F NMR and HRMS. The bioassay results showed that compounds 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-7-methoxybenzo[d][1–3]triazin-4(3H)-one, 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-6-nitrobenzo[d][1–3]triazin-4(3H)-one, 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one exhibited good control efficacy against the cucumber root-knot nematode disease caused by Meloidogyne incognita at the concentration of 10.0 mg L?1 in vivo. Compound 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one showed excellent nematicidal activity with inhibition 68.3% at a concentration of 1.0 mg L?1. It suggested that the structure of 1,2,3-benzotriazin-4-one containing 4,5-dihydro-thiazole-2-thiol could be optimized further.

Pyridazinedione compounds useful in treating neurological disorders

The present invention relates to pyridazino[4,5-b]quinolines, and pharmaceutically useful salts thereof, which are excitatory amino acid antagonists and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides pharmaceutical compositions containing pyridazino[4,5-b]quinolines as active ingredient, and methods for the treatment of neurological disorders.