20776-54-9

Basic information

• Product Name: 2-AMINO-4-IODOBENZOIC ACID
• Synonyms: 2-AMINO-4-IODOBENZOIC ACID
• CAS NO: 20776-54-9
• Molecular Formula: C₇H₆INO₂
• Molecular Weight: 263.03251
• Mol File: 20776-54-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 208 °C (decomp)(Solv: ethanol (64-17-5))
• Boiling Point: 377.02 °C at 760 mmHg
• Flash Point: 181.815 °C
• Appearance: /
• Density: 2.082 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.728
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.76±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-IODOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-IODOBENZOIC ACID(20776-54-9)
• EPA Substance Registry System: 2-AMINO-4-IODOBENZOIC ACID(20776-54-9)

Safety Data

• Hazardous Substances Data: 20776-54-9(Hazardous Substances Data)

Usage

General Description

2-Amino-4-iodobenzoic acid is a chemical compound with the molecular formula C7H6INO2. It is an organic compound that contains both amino and carboxylic acid functional groups. The compound is commonly used in the synthesis of pharmaceuticals, dyes, and agrochemicals. It has been studied for its potential anti-inflammatory and antiviral properties and has demonstrated significant potential in the development of new drugs. Additionally, 2-Amino-4-iodobenzoic acid is used as a reagent in organic synthesis and as a building block for the creation of more complex molecules.

InChI:InChI=1/C7H6INO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,9H2,(H,10,11)

Upstream product

• 20780-77-2 6-iodoisatin 
• 41252-97-5 4-iodo-2-nitrotoluene 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 118-92-3 anthranilic acid 
• 116529-62-5 4-iodo-2-nitro benzoic acid 

Downstream Products

• 35674-29-4 2-amino-4,5-diiodo-benzoic acid 
• 1241915-19-4 (4-(1H-pyrazol-3-ylamino)-7-iodoquinazolin-2-yl)(4-fluorophenyl)methanone 
• 1241915-24-1 (R,S)-(4-(1H-pyrazol-3-ylamino)-7-iodoquinazolin-2-yl)(4-fluorophenyl)methanol 
• 1449276-39-4 4-iodo-2-(5,6,7-trimethoxyquinazolin-4-ylamino)benzoic acid hydrochloride 
• 1428336-95-1 7-iodo-3-cyano-4-hydroxyquinoline 
• 115081-94-2 7-iodo-1H-benz[d][1,3]oxazine-2,4-dione 
• 1093191-13-9 (S)-methyl 3-tert-butoxycarbonylamino-2-(7-((4-(morpholinomethyl)phenyl)ethynyl)-4-oxoquinazolin-3(4H)-yl)propanoate 
• 1093191-14-0 (S)-3-amino-N-hydroxy-2-(7-((4-(morpholinomethyl)phenyl)ethynyl)-4-oxoquinazolin-3(4H)-yl)propanamide 
• 202197-77-1 4-hydroxy-7-iodoquinazoline 
• 202197-78-2 4-chloro-7-iodoquinazoline 

Relevant articles and documents

Novel quinazoline-containing compound, and intermediate and application thereof

The present invention discloses a quinazoline-containing compound having the formula (IA), (IB) or (IC), or a pharmaceutically acceptable salt or a prodrug molecule thereof. The compound is suitable for use as an Aurora kinase inhibitor and is thus suitable for the treatment of Aurora-mediated diseases characterized by excessive or abnormal cell proliferation, for example, cancer.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.