115085-77-3

Upstream product

• 115085-47-7 5-Ethoxy-3-hept-(Z)-ylidene-2-phenyl-tetrahydro-furan 
• 115085-31-9 [1-(2-Bromo-1-ethoxy-ethoxy)-non-2-ynyl]-benzene 
• 115085-24-0 1-phenylnon-2-yn-1-ol 
• 629-27-6 1-Iodooctane 
• 154581-55-2 (E/Z)-1-benzyloxy-3-(4-tolylsulfonyl)decene 
• 84314-22-7 1-methyl-4-(octane-1-sulfonyl)benzene 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

(Alkoxyallyl)sulfones as enal and enone β-anion equivalents. Synthesis of mono-, di- and trisubstituted furans

Treatment of variously-substituted (alkoxyallyl)sulfones 1, 7-9 with strong base followed by aldehydes gives alcohol adducts 5. These may be converted into a wide range of substituted furans 6 by exposure to acid, or to silica gel in dichloromethane containing sulfuric acid in some cases.

1-Benzyloxy-3-(p-tolylsulfonyl)alkenes as enal β-anion equivalents. Synthesis of 2,3-disubstituted furans

An efficient three-step method is described for the synthesis of 2,3-disubstituted furans from (p-tolylsulfonyl)alkanes 6 and 2-benzyloxyethanal.

A SIMPLE SYNTHESIS OF 2,3-DISUBSTITUED FURANS

A general, three step synthesis of 2,3-disubstituted furans via the radical cyclisation of bromoacetal 3 to 2-ethoxy-4-alkylidene tetrahydrofuran (4) is described.