115115-22-5

Upstream product

• 126721-03-7 (4α,5β)-4,5-dihydro-5-(2-hydroxy-1-methylethyl)-4-methyl-2(3H)-furanone 
• 103576-61-0 4(S)-methyl-5(R)-<1(S)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>-dihydro-2(3H)furanone 
• 110410-93-0 3-carbomethoxy-4(S)-methyl-5(R)-<1(S)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>dihydro-2(3H)-furanone 
• 108-24-7 acetic anhydride 
• 115115-21-4 3(R)-<1(S),4-dimethyl-2-(E)-pentenyl>-4(R)-methyl-5-(S)-<1(R)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>-dihydro-2(3H)-furanone 
• 917-54-4 methyllithium 
• 110410-93-0 (4S,5S)-5-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-4-methyl-2-oxo-tetrahydro-furan-3-carboxylic acid methyl ester 
• 412342-76-8 (4S,5S)-5-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-4-methyl-dihydro-furan-2-one 
• 126720-95-4 4(S)-<1(S)-Methyl-2-cyanoethyl>-2,2,5(R)-trimethyl-1,3-dioxane 
• 115047-24-0 (4S,5S)-5-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-((E)-(R)-1,4-dimethyl-pent-2-enyl)-4-methyl-2-oxo-tetrahydro-furan-3-carboxylic acid methyl ester 
• 115047-24-0 (4S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-((E)-(R)-1,4-dimethyl-pent-2-enyl)-4-methyl-2-oxo-tetrahydro-furan-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Total Synthesis of (-)-Denticulatins A and B: Marine Polypropionates from Siphonaria denticulata

A synthesis of the marine polypropionates (-)-denticulatin A (2a) and B (2b) is described.The targets, which are β-hydroxy ketones wherein the hydroxyl group is also a tertiary hemiketal, are sensitive to acid dehydration.An open chain form (26) of the de

Formal Synthesis of (-)-Calcimycin (A-23187) via the 3-Methyl-γ-butyrolactone Approach

A synthesis of (+)-carboxylic acid 2a, which has been previously converted into the ionophore (-)-calcimycin (A-23187) and analogues thereof, is described.The synthesis involves the use of (S)-3-methyl-γ-butyrolactone (4) and both enantiomers of allylic alcohol 3a as the chiral entities.