115118-04-2

Basic information

• Product Name: trans-4-Methylthio-5,6-dihydro-3-phenyl-6-<(trimethylsilyl)methyl>-4H-1,2-oxazine
• CAS NO: 115118-04-2
• Molecular Weight: 293.505
• Mol File: 115118-04-2.mol

Chemical Properties

• CAS DataBase Reference: trans-4-Methylthio-5,6-dihydro-3-phenyl-6-<(trimethylsilyl)methyl>-4H-1,2-oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Methylthio-5,6-dihydro-3-phenyl-6-<(trimethylsilyl)methyl>-4H-1,2-oxazine(115118-04-2)
• EPA Substance Registry System: trans-4-Methylthio-5,6-dihydro-3-phenyl-6-<(trimethylsilyl)methyl>-4H-1,2-oxazine(115118-04-2)

Safety Data

• Hazardous Substances Data: 115118-04-2(Hazardous Substances Data)

Upstream product

• 624-92-0 Dimethyldisulphide 
• 109925-98-6 6-(Trimethylsilyl)methyl-3-phenyl-5,6-dihydro-4H-1,2-oxazine 

Relevant articles and documents

Lithiated 5,6-Dihydro-4H-1,2-oxazines: Synthesis, Highly Diastereoselective Reactions with Electrophiles, and Subsequent Transformations

The 6-(trimethylsilyl)methyl-substituted 1,2-oxazine 1 can smoothly be deprotonated with n-butyllithium at C-4 to give a lithiated species which reacts with a variety of electrophiles to provide the new 1,2-oxazines 5-16 in good yields.Besides the prepara

Highly Diastereoselective Deprotonation and Substitution of Chiral 5,6-Dihydro-4H-1,2-oxazines

Deprotonation of the chiral 1,2-oxazine 1 by n-butyllithium provides a carbanion which reacts highly diastereoselectively with electrophiles affording the substituted 1,2-oxazines 2.The overall substitution occurs under retention of configuration in most cases investigated.These remarkable results are in accord with recent ab initio calculations.