115126-35-7

Upstream product

• 61020-56-2 2-(2-oxo-1,2-dihydro-quinolin-3-yl)-N-p-tolyl-acetamide 
• 53244-92-1 (2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid 
• 4945-33-9 3H-Furo[2,3-b]quinolin-2-one 
• 106-49-0 p-toluidine 
• 188581-87-5 2-(4-azido-1-Z-butenyl)-N-(triphenylphosphoranylidene)aniline 
• 622-58-2 p-Tolylisocyanate 
• 188581-90-0 [3-(2-Azido-ethyl)-quinolin-2-yl]-p-tolyl-amine 
• 61020-59-5 2-chloro-1-p-tolyl-1H-pyrrolo[2,3-b]quinoline 

Relevant academic research and scientific papers

A new entry to the preparation of pyrrolo[2,3-b]quinolines by an aza Wittig/electrocyclic ring-closure/nitrene insertion process

A new method for the preparation of the pyrrolo[2,3-b]quinoline ring system involving the sequential formation of the pyridine ring (elcctrocyclic ring-closure) and the pyrrole (nitrene insertion reaction) rings. This approach is based on the regioselective formation of the iminophosphorane 2 from the bis(azide) 1, followed by aza Wittig reaction with isocyanates and further thermal treatment.

Pyrroloquinolines: Part IV - Synthesis of 1-Aryl-1H-pyrroloquinolines

A wide variety of 1-aryl-2-chloro-1H-pyrroloquinolines (3) have been synthesized by cyclocondensation of 2-quinolone-3-acetanilides (2) with phosphoryl chloride.The chloropyrroloquinolines on hydrogenolysis afford the corresponding pyrroloquinoline