115126-41-5

Upstream product

• 61020-59-5 2-chloro-1-p-tolyl-1H-pyrrolo[2,3-b]quinoline 
• 552-89-6 2-nitro-benzaldehyde 
• 16714-25-3 2-azidobenzaldehyde 
• 622-58-2 p-Tolylisocyanate 
• 106-49-0 p-toluidine 
• 53244-92-1 (2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid 
• 4945-33-9 3H-Furo[2,3-b]quinolin-2-one 

Relevant academic research and scientific papers

Synthesis of 2,3-Disubstituted Quinolines via Ketenimine or Carbodiimide Intermediates

Cyclopenta[b]quinolines and cyclohexa[b]quinolines were prepared via the reactions of α-diazo ketones with N-(2-cyclopropylidenemethylphenyl)phosphanimines and N-(2-cyclobutylidenemethylphenyl) phosphanimine, respectively. The reaction proceeds in a cascade involving ketenimine formation, 6 π-electron ring closure, and 1,3-alkyl shift. A similar approach was developed for the synthesis of dihydropyrrolo-[2,3-b]quinolines from N-(2-cyclopropylidenemethylphenyl)phosphanimines and isocyanates.

Pyrroloquinolines: Part IV - Synthesis of 1-Aryl-1H-pyrroloquinolines

A wide variety of 1-aryl-2-chloro-1H-pyrroloquinolines (3) have been synthesized by cyclocondensation of 2-quinolone-3-acetanilides (2) with phosphoryl chloride.The chloropyrroloquinolines on hydrogenolysis afford the corresponding pyrroloquinoline