115149-50-3Relevant academic research and scientific papers
Low molecular weight non-peptide mimics of ω-conotoxin GVIA
Duggan, Peter J.,Lewis, Richard J.,Phei Lok,Lumsden, Natalie G.,Tuck, Kellie L.,Yang, Aijun
supporting information; experimental part, p. 2763 - 2765 (2009/12/31)
We report the synthesis and biological activity of a low molecular weight non-peptidic mimic of the analgesic peptide ω-conotoxin GVIA. The molecular weight of this compound presents a reduction by 193 g/mol compared to a previously reported lead. This co
SYNTHESIS OF NOVEL MACROCYCLIC LACTONES WITH POTENTIAL PHARMACOLOGICAL ACTIVITY
Smith, Keith,Morris, Ian K.,Owen, Philip G.,Bass, Robert J.
, p. 77 - 84 (2007/10/02)
The total syntheses of four 14-membered ring lactones, (1a), (2a), (22), and (23), are described.The starting materials are the appropriate 2-hydroxybenzoic or (2-hydroxyphenyl)acetic acids and the final step in each case involves lactonization using a mo
