1151893-81-0

Basic information

• Product Name: (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
• Synonyms: (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid;2-[2-[[(5-Chloro-2-thienyl)carbonyl][4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]acetic Acid
• CAS NO: 1151893-81-0
• Molecular Formula: C₂₄H₂₁Cl₂N₃O₇S₂
• Molecular Weight: 598.47544
• EINECS: -0
• Mol File: 1151893-81-0.mol

Chemical Properties

• Boiling Point: 843.9±65.0 °C(Predicted)
• Appearance: /
• Density: 1.542±0.06 g/cm3(Predicted)
• PKA: 3.37±0.10(Predicted)
• CAS DataBase Reference: (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid(1151893-81-0)
• EPA Substance Registry System: (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid(1151893-81-0)

Safety Data

• Hazardous Substances Data: 1151893-81-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid is used as a potential drug candidate or pharmacological tool due to its complex structure and the presence of functional groups that may interact with biological systems.
Used in Medicinal Chemistry Research:
(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid serves as a valuable subject for medicinal chemistry research, where its diverse structural elements and potential interactions with biological systems can be further explored and harnessed for the development of new therapeutic agents.

Upstream product

• 366789-02-8 Rivaroxaban 
• 42518-98-9 5-chlorothiophene-2-carbonyl chloride 
• 931204-39-6 2-[2-({4-[(5S)-5-{[(5-chlorothiophen-2-yl)formamido]methyl}-2-oxo-1,3-oxazolidin-3-yl]phenyl}amino)ethoxy]acetic acid 
• 482308-02-1 N-{[(5S)-3-(4-aminophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}-5-chloro-2-thiophenecarboxamide 
• 1082937-62-9 C₂₀H₂₂ClN₃O₅S 
• 1082937-60-7 C₁₅H₂₁N₃O₄ 
• 931117-61-2 2-({4-[(5S)-5-({[(5-chloro-2-thienyl)carbonyl]amino}methyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-amino)ethoxyacetic acid hydrochloride 
• 19298-14-7 4-di[(2-hydroxyethyl)amino]-aniline 
• 24065-33-6 5-Chlorothiophene-2-carboxylic acid 

Relevant articles and documents

A [...] related substance diamine synthesis method

The invention relates to a rivaroxaban related substance diamine which can be used as a reference substance to research and control rivaroxaban. The preparation method is simple, and the raw materials are easily available. The structural formula of the diamine is shown as follows: FORMULA shown in the description and the formula is C25H24CL2N4O4S2, and the molecular weight is 610.5. The rivaroxaban related substance diamine provided by the invention can be used as a reference substance for monitoring impurities of the rivaroxaban. The synthetic method for the rivaroxaban related substance diamine provided by the invention is simple to operate, has excellent practicality, and can bringrelatively good economic and social benefits.

A related substance [...] F, G synthetic method

The invention provides synthetic methods of related substances F and G of rivaroxaban. With the adoption of the synthetic methods of the related substances F and G of the rivaroxaban, the yield is high, and industrial production and technology transformation are realized easily.

Rivaroxaban impurities and preparing method and application thereof

The invention discloses rivaroxaban impurities. The rivaroxaban impurities include the rivaroxaban impurity 6, the rivaroxaban impurity 10, the rivaroxaban impurity 11 and the rivaroxaban impurity 12; in addition, the invention discloses a preparing method and application of the rivaroxaban impurities. By means of the rivaroxaban impurities and the preparing method thereof, the basis is consolidated for rivaroxaban midbodies and raw material medicine and quality researching of compositions of the rivaroxaban impurities. The structural formula is shown in the specification.

2-Aminoethoxyacetic Acid Derivatives and Their Use

The present application relates to novel 2-aminoethoxyacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular thromboembolic disorders.