931204-39-6

Basic information

• Product Name: Rivaroxaban iMpurity A
• Synonyms: Rivaroxaban iMpurity A;Rivaroxaban Impurity 15;2-({4-[(5S)-5-({[(5-chloro-2-thienyl)carbonyl]amino}methyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-amino)ethoxyacetic acid
• CAS NO: 931204-39-6
• Molecular Formula: C₁₉H₂₀ClN₃O₆S
• Molecular Weight: 453.8966
• Mol File: 931204-39-6.mol

Chemical Properties

• Boiling Point: 736.8±60.0 °C(Predicted)
• Appearance: /
• Density: 1.470±0.06 g/cm3(Predicted)
• PKA: 3.25±0.10(Predicted)
• CAS DataBase Reference: Rivaroxaban iMpurity A(CAS DataBase Reference)
• NIST Chemistry Reference: Rivaroxaban iMpurity A(931204-39-6)
• EPA Substance Registry System: Rivaroxaban iMpurity A(931204-39-6)

Safety Data

• Hazardous Substances Data: 931204-39-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Rivaroxaban iMpurity A is used as a reference compound for the development and quality control of Rivaroxaban, an antithrombotic agent. It helps in ensuring the purity, potency, and safety of the final drug product by providing a benchmark for comparison and analysis. This impurity is essential for the identification, quantification, and control of impurities in the manufacturing process, ultimately contributing to the overall quality and efficacy of Rivaroxaban as a therapeutic agent.

Upstream product

• 366789-02-8 Rivaroxaban 
• 931117-61-2 2-({4-[(5S)-5-({[(5-chloro-2-thienyl)carbonyl]amino}methyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-amino)ethoxyacetic acid hydrochloride 

Downstream Products

• 1807455-76-0 C₂₅H₂₄Cl₂N₄O₆S₂ 
• 1151893-81-0 2-{2-[1-(5-chlorothiophen-2-yl)-N-{4-[(5S)-5-{[(5-chlorothiophen-2-yl)formamido]methyl}-2-oxo-1,3-oxazolidin-3-yl]phenyl}formamido]ethoxy}acetic acid 

Relevant articles and documents

A [...] related substance diamine synthesis method

The invention relates to a rivaroxaban related substance diamine which can be used as a reference substance to research and control rivaroxaban. The preparation method is simple, and the raw materials are easily available. The structural formula of the diamine is shown as follows: FORMULA shown in the description and the formula is C25H24CL2N4O4S2, and the molecular weight is 610.5. The rivaroxaban related substance diamine provided by the invention can be used as a reference substance for monitoring impurities of the rivaroxaban. The synthetic method for the rivaroxaban related substance diamine provided by the invention is simple to operate, has excellent practicality, and can bringrelatively good economic and social benefits.

2-Aminoethoxyacetic Acid Derivatives and Their Use

The present application relates to novel 2-aminoethoxyacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular thromboembolic disorders.