1151903-44-4Relevant academic research and scientific papers
A chemoenzymatic synthesis of 5a-carba-α-D-mannose-6-phosphate
Williams, Paula M.,Sheldrake, Gary N.,Macdonald, Simon J.F.,Hamilton, Chris J.
, p. 1257 - 1261 (2011/07/09)
An efficient chemical synthesis of 5a-carba-α-D-mannose and its enzymatic elaboration to 5a-carba-α-D-mannose-6-phosphate, using yeast hexokinase, is described.
Chemoenzymatic syntheses of carbasugar analogues of nucleoside diphosphate sugars: UDP-carba-Gal, UDP-carba-GlcNAc, UDP-carba-Glc, and GDP-carba-Man
Seo, Kyung-Chang,Kwon, Young-Geol,Kim, Dae-Hee,Jang, In-Sook,Cho, Jin-Won,Chung, Sung-Kee
supporting information; experimental part, p. 1733 - 1735 (2009/08/08)
Chemoenzymatic syntheses of several NDP-carba-sugars have been successfully carried out, and these essential cofactor analogues are expected to be selective inhibitors of glycosyltransferase enzymes. The Royal Society of Chemistry.
