1152-23-4Relevant academic research and scientific papers
Hypervalent iodine catalyzed generation of nitrile oxides from oximes and their cycloaddition with alkenes or alkynes
Yoshimura, Akira,Middleton, Kyle R.,Todora, Anthony D.,Kastern, Brent J.,Koski, Steven R.,Maskaev, Andrey V.,Zhdankin, Viktor V.
, p. 4010 - 4013 (2013/09/02)
Hypervalent iodine catalyzed oxidation of aldoximes using oxone as a terminal oxidant generates nitrile oxides, which react with alkenes and alkynes to give the corresponding isoxazolines and isoxazoles in moderate to good yields. This reaction involves active hypervalent iodine species formed in situ from catalytic iodoarene and oxone in the presence of hexafluoroisopropanol in aqueous methanol solution.
Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant
Yoshimura, Akira,Zhu, Chenjie,Middleton, Kyle R.,Todora, Anthony D.,Kastern, Brent J.,Maskaev, Andrey V.,Zhdankin, Viktor V.
supporting information, p. 4800 - 4802 (2013/06/05)
Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.
