1152162-15-6Relevant articles and documents
8-Aza-7-deazaguanine nucleosides and oligonucleotides with octadiynyl side chains: Synthesis, functionalization by the azide-alkyne 'click' reaction and nucleobase specific fluorescence quenching of coumarin dye conjugates
Seela, Frank,Xiong, Hai,Leonard, Peter,Budow, Simone
, p. 1374 - 1387 (2009)
Oligonucleotides incorporating 7-(octa-1,7-diynyl) derivatives of 8-aza-7-deaza-2′-deoxyguanosine (2d) were prepared by solid-phase synthesis. The side chain of 2d was introduced by the Sonogashira cross coupling reaction and phosphoramidites (3a, 3b) wer