1152427-91-2Relevant academic research and scientific papers
Amphoteric α-boryl aldehydes
He, Zhi,Yudin, Andrei K.
supporting information; experimental part, p. 13770 - 13773 (2011/10/05)
A new class of stable molecules, α-boryl aldehydes, has been prepared from oxiranyl N-methyliminodiacetyl boronates by a 1,2-boryl migration with concomitant epoxide scission. A range of boryl imines, alkenes, alcohols, acids, enol ethers, enamides, and other functionalized boronic acid derivatives that are difficult or impossible to prepare using established protocols can be accessed from α-boryl aldehydes. The chemoselective transformations of these building blocks, including the facile synthesis of functionalized unnatural amino acids from silyloxy and amido vinyl boronates, attest to the potential of α-boryl aldehydes in chemical synthesis.
Vinyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis
Uno, Brice E.,Gillis, Eric P.,Burke, Martin D.
experimental part, p. 3130 - 3138 (2009/09/05)
Iterative cross-coupling represents a potentially general approach for the simple, efficient, and flexible construction of natural products, pharmaceuticals, and materials. N-Methyliminodiacetic acid (MIDA) boronates represent a promising platform for the
