115250-18-5Relevant articles and documents
Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase
Takahashi, Masato,Uehara, Tomoki,Nonaka, Minori,Minagawa, Yuka,Yamazaki, Riona,Haba, Masami,Hosokawa, Masakiyo
, p. 125 - 131 (2019)
Two types of haloperidol prodrugs in which a chemical modification was carried out on the hydroxyl group or carbonyl group were synthesized, and their metabolic activation abilities were evaluated in a human liver microsome (HLM) solution, a human small i
PROTEASE-BINDING COMPOUNDS AND METHODS OF USE
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, (2008/06/13)
Non-peptide, protease-binding compounds are described as useful in the detection, labelling, and inhibition of retroviral proteases. Aryl piperidinyl derivatives and other compounds related in structure have been found to be HIV-1 and HIV-2 protease-binding compounds.