115255-07-7Relevant academic research and scientific papers
FOLATE DERIVATIVES, USEFUL IN PARTICULAR IN THE CONTEXT OF THE FOLATE ASSAY
-
Paragraph 0237, (2018/07/05)
Use of a folate derivative to assay in vitro the folate in a sample such as a biological sample.
Self-assembly of thermotropic liquid-crystalline folic acid derivatives: Hydrogen-bonded complexes forming layers and columns
Kanie,Nishii,Yasuda,Taki,Ujiie,Kato
, p. 2875 - 2886 (2007/10/03)
Folic acid derivatives having 2-(3,4-dialkoxyphenyl)ethyl moieties have been found to exhibit thermotropic liquid-crystalline behavior. Smectic and discotic phases are observed for these compounds over wide temperature ranges. X-Ray diffraction and infrar
Synthesis and evaluation of pteroic acid-conjugated nitroheterocyclic phosphoramidates as folate receptor-targeted alkylating agents
Steinberg,Borch
, p. 69 - 73 (2007/10/03)
A novel nitroheterocyclic bis(haloethyl)phosphoramidate prodrug linked through lysine to a pteroic acid has been prepared and evaluated as a potential alkylating agent to target tumor cells that overexpress the folate receptor. The prodrug exhibited ICsu
Folate analogues. 33. Synthesis of folate and antifolate poly-γ-glutamates by [(9-fluorenylmethoxy)oxy]carbonyl chemistry and biological evaluation of certain methotrexate polyglutamate polylysine conjugates as inhibitors of the growth of H35 hepatoma cel
Abraham,Nair,Kisliuk,Gaumont,Galivan
, p. 711 - 717 (2007/10/02)
Representative examples of folate and antifolate poly-γ-glutamyl metabolites were synthesized via the [(9-fluorenylmethoxy)oxy]carbonyl (Fmoc) chemistry using the KH polyamide resin. Polyglutamate yields were consistently better in all cases compared to t
