324770-56-1

Basic information

• Product Name: (5-nitro-2-furyl)methyl N^ε-(N¹⁰-(trifluoroacetyl)pteroyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate
• Synonyms: (5-nitro-2-furyl)methyl N^ε-(N¹⁰-(trifluoroacetyl)pteroyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate
• CAS NO: 324770-56-1
• Molecular Weight: 865.547
• Mol File: 324770-56-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5-nitro-2-furyl)methyl N^ε-(N¹⁰-(trifluoroacetyl)pteroyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate(CAS DataBase Reference)
• NIST Chemistry Reference: (5-nitro-2-furyl)methyl N^ε-(N¹⁰-(trifluoroacetyl)pteroyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate(324770-56-1)
• EPA Substance Registry System: (5-nitro-2-furyl)methyl N^ε-(N¹⁰-(trifluoroacetyl)pteroyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate(324770-56-1)

Safety Data

• Hazardous Substances Data: 324770-56-1(Hazardous Substances Data)

Upstream product

• 324770-54-9 (5-nitro-2-furyl)methyl N^ε-(O-allyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate 
• 324770-49-2 (5-nitro-2-furyl)methyl N^ε-(O-methyllysyl)-N,N-bis(2-chloroethyl)phosphorodiamidate 
• 13515-95-2 lysine methyl ester dihydrochloride 
• 37793-53-6 N₁₀-trifluoroacetylpteroic acid 
• 324770-51-6 (5-nitro-2-furyl)methyl N^ε-lysyl-N,N-bis(2-chloroethyl)phosphorodiamidate 
• 115255-07-7 C₂₁H₁₉F₃N₆O₆ 

Relevant articles and documents

Synthesis and evaluation of pteroic acid-conjugated nitroheterocyclic phosphoramidates as folate receptor-targeted alkylating agents

A novel nitroheterocyclic bis(haloethyl)phosphoramidate prodrug linked through lysine to a pteroic acid has been prepared and evaluated as a potential alkylating agent to target tumor cells that overexpress the folate receptor. The prodrug exhibited ICsu