1152629-53-2Relevant academic research and scientific papers
1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl] sulfanyl}acetanilides as HIV-1 inhibitors
Zhan, Peng,Liu, Xin-Yong,Li, Zhen-Yu,Fang, Zeng-Jun,Pannecouque, Christophe,De Clercq, Erik
, p. 1717 - 1727 (2010)
As part of our studies to discover new HIV-1 reverse transcriptase inhibitors, a series of 3,4-dichlorophenyl substituted 1,2,3-thiadiazole thioacetanilide (TTA=[(1,2,3-thiadiazole-5-yl)sulfanyl]-acetanilide) derivatives were synthesized, and in vitro ant
1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation
Zhan, Peng,Liu, Xinyong,Fang, Zengjun,Pannecouque, Christophe,Clercq, Erik De
experimental part, p. 6374 - 6379 (2011/02/25)
The development of new HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) offers the possibility of generating novel structures of increased potency. Based on the bioisosteric principle, novel series of 1,2,3-selenadiazole thioacetanilide deri
