1152961-33-5

Basic information

• Product Name: N-(cyclohexylmethyl)-[1,1′-biphenyl]-4-amine
• CAS NO: 1152961-33-5
• Molecular Weight: 265.398
• Mol File: 1152961-33-5.mol

Chemical Properties

• CAS DataBase Reference: N-(cyclohexylmethyl)-[1,1′-biphenyl]-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(cyclohexylmethyl)-[1,1′-biphenyl]-4-amine(1152961-33-5)
• EPA Substance Registry System: N-(cyclohexylmethyl)-[1,1′-biphenyl]-4-amine(1152961-33-5)

Safety Data

• Hazardous Substances Data: 1152961-33-5(Hazardous Substances Data)

Upstream product

• 92-67-1 4-phenylalanine 
• 110-82-7 cyclohexane 
• 3365-81-9 biphenyl-4-yl-methyl-amine 
• 2043-61-0 cyclohexanecarbaldehyde 
• 586-78-7 para-nitrophenyl bromide 
• 92-93-3 1-phenyl-4-nitrobenzene 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

One-pot procedures for the formation of secondary aryl amines from nitro aryls

Strategies for the one-pot formation of secondary aryl amines from the corresponding nitro aryls by utilizing reductive amination procedures are discussed. The extension of this chemistry where a Suzuki-Miyaura cross-coupling is conducted between a boronic acid and bromonitrobenzene prior to the reductive amination in one-pot is also presented. Georg Thieme Verlag Stuttgart, New York.

Iron-Catalyzed Regioselective α-C-H Alkylation of N-Methylanilines: Cross-Dehydrogenative Coupling between Unactivated C(sp3)-H and C(sp3)-H Bonds via a Radical Process

The iron-catalyzed α-C-H alkylation of N-methylanilines without any directing group by cross-dehydrogenative coupling between unactivated C(sp3)-H and C(sp3)-H bonds has been established for the first time, which provides a good complement to C(sp3)-H activation reactions and expands the field of Fe-catalyzed C-H functionalizations. Many different C(sp3)-H bonds in cyclic alkanes, cyclic ethers, and toluene derivatives can be used as coupling partners. Mechanistic investigations including the radical reaction process, the main role of various reagents, and the kinetic isotope effect experiment were also described.

One-pot Suzuki-Miyaura cross-coupling followed by reductive monoalkylation of the resulting nitro biaryl system utilizing Pd/C as catalyst

Conditions for one-pot Suzuki-Miyaura cross-coupling between aryl boronic acids and bromo-nitrobenzene followed by reductive monoalkylation of the nitro functionality of the biaryl cross-coupling product utilizing hydrogen over Pd/C as the catalyst and aldehydes as alkylation agent are described.