1153-79-3

Usage

Uses

Used in Organic Synthesis:
(4-nitrophenyl)(2,4,6-trimethylphenyl)methanone is used as a synthetic intermediate for the creation of more complex organic molecules. Its versatile structure makes it a valuable component in the synthesis of various compounds, facilitating the development of new materials and chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone is utilized as a building block for the development of new drugs. Its potential biological activities are of interest to researchers, who are exploring its use in the design and synthesis of pharmaceutical agents that could address various medical conditions.
Used in Chemical Research:
(4-nitrophenyl)(2,4,6-trimethylphenyl)methanone is also employed in chemical research to study its properties and reactivity. Understanding how (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone interacts with other chemicals can provide insights into new reaction pathways and mechanisms, contributing to the broader field of chemistry.
While the specific applications and industries for (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone are not explicitly detailed in the provided materials, the general uses outlined above are inferred from its role as a building block in organic synthesis and pharmaceutical research, as well as its potential for biological activity and chemical reactivity studies.

Upstream product

• 902-47-6 p-nitrobenzoic anhydride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 62-23-7 4-nitro-benzoic acid 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 1146-88-9 2.4.6-Trimethyl-4'-amino-thiobenzophenon 
• 1146-85-6 4-aminophenylmesitylketone 

Relevant academic research and scientific papers

Simple and efficient procedure for the friedel-crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/AL2O3 under heterogeneous conditions

An efficient and chemoselective method for the Friedel-Crafts acylation of aromatic compounds using P2O5/Al2O3 and carboxylic acids. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones in good yields.

Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 under heterogeneous conditions

A convenient and efficient procedure for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 is described. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones. The use of non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.

BiCl3-catalyzed Friedel-Crafts acylation reactions: Bismuth(III) oxychloride as a water insensitive and recyclable procatalyst

The Friedel-Crafts acylation of activated and polycyclic aromatics is efficiently catalyzed by bismuth(III) chloride which is generated in situ from bismuth(III) oxychloride, a water insensitive and eco-friendly material. Bismuth(III) oxychloride is easily recovered in near quantitative yields after an aqueous work-up.

High-Throughput Synthesis of Alkylbenzophenones with Indium Triflate in the Absence of Solvents Using Microwave

A series of alkylbenzophenones were rapidly and efficiently prepared from alkylbenzenes and benzoyl chlorides by Friedel-Crafts acylation catalyzed with indium triflate under solvent-free conditions by microwave heating.

Carboxylic Trifluoromethanesulfonic Anhydrides as Highly Effective Acylation Agents. - Perfluoroalkanesulfonic Acid Catalyzed Acylation of Arenes

Arene- and alkanecarboxylic trifluoromethanesulfonic anhydrides 2 and 5 are highly effective acylation agents, which react without Friedel-Crafts catalysts even with deactivated aromatics to yield aryl ketones 3 and 6, respectively.Acylation of arenes with carbonyl chlorides 4 and catalytic amounts of perfluoroalkanesulfonic acid gives ketones 3 and 6, resp., in good yields.Under similar conditions other strong Broensted acids show a considerably smaller degree of catalytic effect.

Acylierung von Aromaten mit Carbonsaeure-dihalogenphosphorsaeure-anhydriden

Aryl ketones 4, 9 are formed in good yields without the addition of Friedel-Crafts catalysts from activated arenes (e. g. alkylbenzenes, anisole) and aryl- and alkylcarboxylic dihalophosphoric anhydrides 1, 2, and 7, 8, respectively.The anhydrides 7, 8 may be prepared in situ by mixing the respective carboxylic and dihalophosphoric anhydrides.This procedure is especially advantageous in care of the less stable compounds.