1153-79-3

Basic information

• Product Name: (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone
• CAS NO: 1153-79-3
• Molecular Formula: C₁₆H₁₅NO₃
• Molecular Weight: 269.2952
• Mol File: 1153-79-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 395.8°C at 760 mmHg
• Flash Point: 176.9°C
• Density: 1.18g/cm³
• Vapor Pressure: 1.79E-06mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone(1153-79-3)
• EPA Substance Registry System: (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone(1153-79-3)

Safety Data

• Hazardous Substances Data: 1153-79-3(Hazardous Substances Data)

Usage

General Description

"(4-nitrophenyl)(2,4,6-trimethylphenyl)methanone" is a chemical compound with the molecular formula C15H13NO3. It is a ketone derivative and consists of a 4-nitrophenyl group and a 2,4,6-trimethylphenyl group attached to a methanone functional group. (4-nitrophenyl)(2,4,6-trimethylphenyl)methanone is often used in organic synthesis and pharmaceutical research as a building block for more complex molecules. It has the potential to exhibit various properties and has been studied for its potential biological activities. Additionally, it is important to note that the compound should be handled and used with caution, as it may pose certain safety and health hazards.

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 62-23-7 4-nitro-benzoic acid 
• 902-47-6 p-nitrobenzoic anhydride 

Downstream Products

• 1146-88-9 2.4.6-Trimethyl-4'-amino-thiobenzophenon 
• 1146-85-6 4-aminophenylmesitylketone 

Relevant articles and documents

Simple and efficient procedure for the friedel-crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/AL2O3 under heterogeneous conditions

An efficient and chemoselective method for the Friedel-Crafts acylation of aromatic compounds using P2O5/Al2O3 and carboxylic acids. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones in good yields.

BiCl3-catalyzed Friedel-Crafts acylation reactions: Bismuth(III) oxychloride as a water insensitive and recyclable procatalyst

The Friedel-Crafts acylation of activated and polycyclic aromatics is efficiently catalyzed by bismuth(III) chloride which is generated in situ from bismuth(III) oxychloride, a water insensitive and eco-friendly material. Bismuth(III) oxychloride is easily recovered in near quantitative yields after an aqueous work-up.

Carboxylic Trifluoromethanesulfonic Anhydrides as Highly Effective Acylation Agents. - Perfluoroalkanesulfonic Acid Catalyzed Acylation of Arenes

Arene- and alkanecarboxylic trifluoromethanesulfonic anhydrides 2 and 5 are highly effective acylation agents, which react without Friedel-Crafts catalysts even with deactivated aromatics to yield aryl ketones 3 and 6, respectively.Acylation of arenes with carbonyl chlorides 4 and catalytic amounts of perfluoroalkanesulfonic acid gives ketones 3 and 6, resp., in good yields.Under similar conditions other strong Broensted acids show a considerably smaller degree of catalytic effect.