1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester, commonly known as Eticlopride, is a pyridinecarboxylic acid derivative with significant pharmacological and therapeutic potential. Structurally related to dopamine antagonists, Eticlopride functions as a selective dopamine D2 receptor antagonist. Its capacity to bind to and modulate dopamine receptors positions it as a valuable compound for research and drug development, particularly in the realms of neuroscience and psychopharmacology.
1153-83-9
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Basic information
- Product Name: 1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester
- Synonyms: 1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester;3-Pyridinecarboxylic acid,1,6-dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-,ethyl ester
- CAS NO:1153-83-9
- Molecular Formula: C15H15NO4
- Molecular Weight: 273.28
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1153-83-9.mol
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Chemical Properties
- Melting Point: 175 °C
- Boiling Point: 388.4±42.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.302±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 4.50±1.00(Predicted)
- CAS DataBase Reference: 1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: 1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester(1153-83-9)
- EPA Substance Registry System: 1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester(1153-83-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1153-83-9(Hazardous Substances Data)
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1153-83-9 Usage
Uses
Used in Pharmaceutical Industry:Eticlopride is utilized as a therapeutic agent for the treatment of various neurological and psychiatric disorders. Its selective antagonism of dopamine D2 receptors makes it a promising candidate for conditions such as schizophrenia, Parkinson's disease, and drug addiction. The modulation of neurotransmission by Eticlopride offers potential benefits in managing the symptoms and progression of these disorders.
Used in Research Applications:
In the field of neuroscience, Eticlopride serves as a valuable research tool for studying the role of dopamine receptors in cognitive functions and behavioral responses. Its selectivity for the D2 receptor subtype allows for targeted investigation into the mechanisms underlying neurological and psychiatric conditions, contributing to a deeper understanding of these complex diseases and the development of more effective treatments.
Used in Drug Development:
Eticlopride's pharmacological properties make it a key component in the development of new drugs aimed at treating disorders associated with dopamine dysregulation. Its potential to modulate neurotransmission and alleviate symptoms of various neurological and psychiatric conditions positions Eticlopride as a significant asset in the quest for novel therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 1153-83-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,5 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1153-83:
(6*1)+(5*1)+(4*5)+(3*3)+(2*8)+(1*3)=59
59 % 10 = 9
So 1153-83-9 is a valid CAS Registry Number.
1153-83-9Upstream product
1153-83-9Downstream Products
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1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester
