115307-41-0Relevant academic research and scientific papers
Controlled and efficient synthesis of quinoline derivatives from Morita-Baylis-HILLMAN adducts by palladium-catalyzed heck reaction and cyclization
Selvakumar, Kodirajan,Lingam, Kandapalam Arun Prasath,Varma, Rama Varma Luxmi,Vijayabaskar, Veerappan
supporting information, p. 646 - 650 (2015/03/14)
An efficient synthesis of 2,3-disubstituted quinoline derivatives from easily accessible (het)aryl-substituted Morita-Baylis-Hillman (MBH) adducts was achieved by an approach involving a palladium-catalyzed Heck reaction and cyclization. This strategy converts the MBH adducts into α-benzyl β-keto ester derivatives that can cyclize into the corresponding quinolines in good yields.
A Convenient Synthesis of Substituted Quinolines by Thermal Electrocyclic Rearrangement of o-Vinyl Anils under Nonacidic Conditions
Qiang, Lin Guo,Baine, Neil H.
, p. 4218 - 4222 (2007/10/02)
Anils 8a-g (Table II) underwent smooth rearrangement and oxidation to the quinolines 9a-g at 155-200 deg C via formation of the 2-3 carbon-carbon bond.These cyclizations proceeded in high yields under nonacidic conditions.It was often possible to prepare
