115351-15-0

Upstream product

• 115351-19-4 Trifluoro-methanesulfonic acid (R)-2-benzyloxy-1-((3aR,5S,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethyl ester 
• 100-39-0 benzyl bromide 
• 130619-55-5 5-azido-5-deoxy-1,2-O-isopropylidene-β-L-idofuranose 
• 81823-12-3 1,2-O-isopropylidene-3,6-di-O-benzyl-α-D-glucofuranose 
• 22529-61-9 (1R)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-5-yl)ethane-1,2-diol 

Downstream Products

• 1395068-28-6 5-azido-3,6-di-O-benzyl-5-deoxy-L-idono-1,4-lactone 
• 1395068-30-0 5-azido-3,6-di-O-benzyl-5-deoxy-2-O-trifluoromethanesulfonyl-L-idono-1,4-lactone 
• 1395068-32-2 3,6-di-O-benzyl-2,5-dideoxy-2,5-imino-L-gulono-1,4-lactone 
• 1395068-33-3 5-azido-3,6-di-O-benzyl-5-deoxy-L-gulono-1,4-lactone 
• 1395068-35-5 5-azido-3,6-di-O-benzyl-5-deoxy-2-O-methanesulfonyl-L-gulono-1,4-lactone 

Relevant academic research and scientific papers

Glycosidase inhibition by all 10 stereoisomeric 2,5-dideoxy-2,5- iminohexitols prepared from the enantiomers of glucuronolactone

The enantiomers of glucuronolactone are excellent chirons for the synthesis of the 10 stereoisomeric 2,5-dideoxy-2,5-iminohexitols by formation of the pyrrolidine ring by nitrogen substitution at C2 and C5, with either retention or inversion of configurat

Synthesis of the antibiotic 1,5-dideoxy-1,5-imino-D-glucitol; concomitant formation of the D-mannitol analogue

The easy accessible 1,2-O-isopropylidene-3-O-benzyl-α-D-glucofuranose was converted in six steps into 1,2-O-isopropylidene-3,6-di-O-benzyl-5-deoxy-5-azido-α-D-glucofuranose.The latter afforded, after acidolysis followed by hydrogenolysis, 1-deoxynojirimicine and a small quantity of 1-deoxymannonojirimicine.The antibiotic thus obtained had an inhibitory effect on the trimming of N-linked carbohydrates in IgM.