1153515-63-9

Upstream product

• 59-31-4 2-quinolone 
• 944-70-7 N-propylquinolin-2(1H)-one 
• 91-22-5 quinoline 
• 39233-36-8 1-n-propylquinolin-1-ium iodide 
• 22246-16-8 6-nitro-3,4-dihydro-1H-quinolin-2-one 
• 553-03-7 3,4-dihydro-2(1H)-quinolone 

Relevant academic research and scientific papers

Preparation method of novel abscisic acid agonist AM1

The invention discloses a preparation method of a novel abscisic acid agonist AM1, and relates to chemical synthesis. The preparation method comprises the following steps: taking cheap quinoline as a raw material, and preparing a key intermediate 1-propyl

Preparation method of N-propyl amino quinolinone and application of N-propyl amino quinolinone to synthesis of abscisic acid agonist AM1 and derivative thereof

The invention discloses a preparation method of N-propyl amino quinolinone and application of the N-propyl amino quinolinone to synthesis of an abscisic acid agonist AM1 and a derivative thereof, which relate to the field of organic synthesis and chemical regulation. By taking quinolinone as an initial raw material, alkylation, nitration and hydrogenation-nitro reduction are conducted to obtain an intermediate 1-propyl-6-amino-3, 4-dihydro-2(1H)-quinolinone, and chemical combination is conducted on p-methylbenzylsulfonyl chloride and the 1-propyl-6-amino-3, 4-dihydro-2(1H)-quinolinone under the action of an acid-binding agent to prepare an abscisic acid agonist AM1. On the other hand, quinolinone is used as a starting raw material, alkylation, nitration and nitro reduction are performed to obtain an intermediate 1-propyl-6-aminohydrogen-2(1H)-quinolinone, and substituted benzyl sulfonyl chloride and the 1-propyl-6-amino-2(1H)-quinolinone are compounded under the action of an acid-binding agent to prepare the agonist AM1 derivative. The method provides a novel strategy for preparing the N-propyl amino quinolinone, the N-propyl amino quinolinone is applied to synthesis of the AM1 and the derivatives of the AM1, deep research, popularization and application of the AM1 and the derivatives of the AM1 are promoted, and the quinolinone is used as a starting raw material, so that the cost is effectively reduced, the practicability is high, and the application value and the economic value are relatively high.

Tetrahydroquinolinyl phosphinamidates and phosphonamidates enhancing tolerance towards drought stress in crops via interaction with ABA receptor proteins

New phosphorous-containing lead structures against drought stress in crops interacting with RCAR/(PYR/PYL) receptor proteins were identified starting from in-depth SAR studies of related sulfonamide lead structures and protein docking studies. A converging 6-step synthesis via phosphinic chlorides and phosphono chloridates as key intermediates afforded envisaged tetrahydroquinolinyl phosphinamidates and phosphonamidates. Whilst tetrahydroquinolinyl phosphonamidates 13a,b exhibited low to moderate target affinities, the corresponding tetrahydroquinolinyl phosphinamidates 12a,b revealed confirmed strong affinities for RCAR/ (PYR/PYL) receptor proteins in Arabidopsis thaliana on the same level as essential plant hormone abscisic acid (ABA) combined with promising efficacy against drought stress in vivo (broad-acre crops wheat and canola).

Small Molecule Compound for Enhancing Plant Stress Resistance

Disclosed are a small molecule compound for enhancing plant stress resistance, a preparation method therefor, and application thereof. Specifically, disclosed are compounds as shown in formula I, salts thereof, optical isomers thereof, racemes thereof, so

SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS

The invention relates to substituted oxotetrahydroquinolinylphosphin- and -phosphonamides of the general formula (I) and salts thereof where the radicals of the formula (I) are each as defined in the description for enhancing stress tolerance in plants to abiotic stress, and for enhancing plant growth and/or for increasing plant yield.