1153791-09-3Relevant academic research and scientific papers
Synthesis of N-alkyl pyrroles via decarboxylation/dehydration in neutral ionic liquid under catalyst-free conditions
Yadav, Veena D.,Dighe, Shashikant U.,Batra, Sanjay
, p. 57587 - 57590 (2014)
A general route to N-alkyl pyrroles by reacting aromatic, heteroaromatic or aliphatic aldehydes with 4-hydroxyproline in ionic liquid under neutral condition was developed. The ionic liquid can be readily recovered and reused for up to 5 reaction cycles without any effect on the yield of the product formed. The utility of the protocol for the one-pot synthesis of 9H-benzo[e]pyrrolo[2,1-b][1,3]oxazines is also presented.
Decarboxylative formation of N-alkyl pyrroles from 4-hydroxyproline
Deb, Indubhusan,Coiro, Daniel J.,Seidel, Daniel
scheme or table, p. 6473 - 6475 (2011/06/28)
N-Alkyl pyrroles are obtained in a single step from 4-hydroxyproline and aldehydes in just 15 min under microwave irradiation.
