1154060-53-3Relevant academic research and scientific papers
CuI catalyzed domino coupling–cyclization of 2-iodo-phenols and 1-alkynes to the synthesis of 2-substituted benzo[b]furans/furo-pyridines
Chen, Ze-Pin,Zhou, Yi,Shui, Meng-Zhu,Liu, Feng
, p. 133 - 136 (2019)
CuI/proline-catalyzed coupling reaction of 2-iodo-phenols with terminal alkynes and the following cyclization process is carried out successively in DMSO at 80 °C. Under this tandem process, 2-substituted benzo[b]furans/furo-pyridines were synthesized in good to excellent yields with a great diversity.
Copper pincer complexes as advantageous catalysts for the heteroannulation of ortho-halophenols and alkynes
Moure, Maria Jesus,Sanmartin, Raul,Dominguez, Esther
, p. 2070 - 2080 (2014/07/07)
A new, non-symmetrical copper(II) pincer complex catalyzes much more efficiently the formation of benzofuran by the reaction between ortho-iodophenols and alkynes. The lowest catalyst loadings are realized for this reaction, and bromo- and chlorophenols are heteroannulated for the first time. Strong evidence for hydrophenoxylation and intramolecular halogen atom-transfer steps catalyzed by this remarkably active, recyclable homogeneous catalyst is provided.
BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065
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Page/Page column 26, (2009/05/28)
The invention provides compounds of formula wherein R1, R2, R3, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1
BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066
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Page/Page column 40, (2009/06/27)
The invention provides compounds of formula wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.
