115407-44-8

Upstream product

• 96-50-4 2-thiazolylamine 
• 114604-68-1 α-bromo-4-(3-chloropropoxy)acetophenone 
• 99-93-4 4-Hydroxyacetophenone 
• 91427-23-5 1-[4-(3-chloropropoxy)phenyl]ethanone 
• 109-70-6 1.3-chlorobromopropane 
• 266685-19-2 6-(4-Hydroxyphenyl)imidazo[2,1-b]thiazole 

Downstream Products

• 115407-33-5 Dibutyl-[3-(4-imidazo[2,1-b]thiazol-6-yl-phenoxy)-propyl]-amine 

Relevant academic research and scientific papers

Substituted phenoxyalkylpiperazines as dopamine d3 receptor ligands

A novel series of potential antipsychotic agents were prepared by combination of condensed heterocycles containing bridgehead nitrogen with (2-methoxyphenyl)piperazine using phenoxyalkyl spacer of variable length. The affinity of the compounds was determined at rat cloned D3 and rat D2, 5-HT1A receptors by an vitro receptor binding assay. The D3 selectivity of the compounds was calculated from the Ki values.

Synthesis of (aryloxy)alkylamines. 2. Novel imidazo-fused heterocycles with calcium channel blocking and local anesthetic activity

A series of imidazo-fused heterocycles substituted with an (aryloxy)alkylamine side chain were prepared as modifications to butoprozine (I) and found to possess calcium channel blocking activity similar in potency to that of bepridil in trachea smooth mus