115432-06-9Relevant academic research and scientific papers
REGIO- AND STEREOSELECTIVE CONTROL IN THE ALKYLATION OF 1-ALKOXY-1,4-CYCLOHEXADIENES BY THE CHIRAL AUXILIARY APPROACH. ENANTIOSELECTIVE SYNTHESIS OF PRECURSORS FOR CIS-HYDRINDANES.
Stanssens, Dirk,Keukeleire, Denis De,Vandewalle, Maurits
, p. 547 - 560 (2007/10/02)
A method is described for the regio- and diastereoselective alkylation of optically active 1-alkoxy-1,4-cyclohexadienes.Reaction conditions were optimised for substrates 4a with the per-O-methyl-β-D-glucopyranosyl group as chiral auxiliary.In the methylat
CHELATION CONTROLLED REGIOSELECTIVE ALKYLATION AND 1,4 CHIRALITY TRANSFER IN OPTICALLY ACTIVE 1-ALKOXY-1,4-CYCLOHEXADIENES
Stanssens, Dirk,Keukeleire, Denis De,Vandewalle, Maurits
, p. 4195 - 4198 (2007/10/02)
Chelation controlled alkylation of optically active 1-alkoxy-1,4-cyclohexadienes leads to a mixture of 1,4-cyclohexadienes 4a-c and 1,3-cyclohexadienes 5a-c.The regio- and diastereoselectivities depend upon the nature of the chiral auxiliary and the react
