1154414-87-5Relevant academic research and scientific papers
Base-Mediated Oxidative Degradation of Secondary Amides Derived from p-Amino Phenol to Primary Amides in Drug Molecules
Nanda, Kausik K.,Ginnetti, Anthony,Wuelfing, W. Peter
, p. 3394 - 3403 (2020)
One of the most common functional groups encountered in drug molecules is the amide, and the most common degradation pathway for amides is base-mediated hydrolysis to its constituent amine and carboxylic acid. Herein, we report for the first time, a base-
PHARMACEUTICAL COMPOUNDS
-
Page/Page column 93; 147, (2015/09/23)
This invention relates to compounds that inhibit or modulate the activity of Chk-1 kinase. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds.
EQUILIBRATIVE NUCLEOSIDE TRANSPORTER ENT1 INHIBITORS
-
Page/Page column 30-31, (2009/06/27)
The present invention is related to novel compounds of formula (I) having equilibrative nucleoside transporter ENTl inhibiting properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases linked to the inhibition of ENTl receptors in animals, in particular humans.
