1154579-82-4

Usage

Uses

Used in Organic Synthesis:
2,3-difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is used as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its ability to participate in a range of chemical reactions, such as cross-coupling and Suzuki-Miyaura reactions, facilitates the synthesis of diverse organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,3-difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is utilized as a building block for the development of new drugs and pharmaceuticals. Its unique chemical properties allow for the design of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Medicinal Chemistry:
2,3-difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is employed as a reagent in medicinal chemistry to form boron-containing molecules. These molecules have significant applications in the development of new drugs, diagnostics, and imaging agents, owing to their unique chemical and biological properties.
Used in Material Science:
In the field of material science, 2,3-difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is used for the synthesis of advanced materials with specific properties. The incorporation of boron and fluorine atoms into the molecular structure allows for the creation of materials with tailored characteristics for various applications, such as sensors, catalysts, and electronic devices.

Upstream product

• 89402-44-8 5-bromo-2,3-difluoropyridine 
• 73183-34-3 bis(pinacol)diborane 
• 851386-35-1 2,3-difluoro-5-iodopyridine 
• 89402-43-7 5-chloro-2,3-difluoropyridine 

Relevant academic research and scientific papers

COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.

2,3-DIHYDROIMIDAZO[1 ,2-c] PYRIMIDIN-5(1 H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS

Disclosed are 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one compounds that inhibit Lp-PLA2, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.

2,3-DIHYDROIMIDAZO[1,2-C] PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS

Disclosed are 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one compounds that inhibit Lp-PLA2, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer?s disease

IMIDAZOLE DERIVATIVES

Disclosed herein are novel imidazole derivative compounds i.e., benzimidazole and aza-benzimidazole derivatives that act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperiipidemia, diabetes mellitus and obesity. Further disclosed are methods of treating various DGAT1 -related diseases, and the use of such imidazole compounds as described herein in the manufacture of a medicament for such treatment.

HETEROARYLOXY QUINAZOLINE DERIVATIVE

Disclosed are compounds of the following formula and their pharmaceutically-acceptable salts, which have an effect of glucokinase activation and are useful in the field of medicines for treatment for diabetes, obesity, etc. (wherein ring A represents a pyrazolyl group optionally having a lower alkyl group, etc.; ring B represents a heteroaryl group; R represents a lower alkyl group, etc.; R1 represents a group of a formula: (wherein R11 and R12 each independently represent a hydrogen atom, etc.; m indicates an integer of from 2 to 6), etc.; R2 represents a lower alkyl group, etc.; r indicates an integer of from 0 to 3; k indicates an integer of from 0 to 4).