115463-93-9Relevant articles and documents
Biosynthesis of Natural Products with a P-C Bond, IV. - Synthesis of (R)- and (S)-(2-Amino-ethyl)phosphonic Acid and Hydroxylation to (2-Amino-1-hydroxyethyl)phosphonic Acid in Acanthamoeba castellanii (Neff)
Hammerschmidt, Friedrich
, p. 961 - 964 (2007/10/02)
Starting from (S)-(+)-2-(benzyloxy)ethanol (3), (R)-(-)- and (S)-(+)-(2-aminoethyl)phosphonic acid (8) are prepared.The enantiomeric excess as determined by 1H-NMR spectroscopy after derivatisation with (+)-α-(methoxy)-α-(trifluoromethyl)pheny