115464-90-9

Usage

Aromatic ring

Five-membered with one nitrogen atom
The pyrrole ring structure contains five atoms, one of which is a nitrogen atom, giving it unique electronic properties.

Derivative of pyrrole

2-(2,6-difluorophenyl) substitution
The parent compound is pyrrole, and this specific compound has two fluorine atoms attached to the phenyl ring at the 2 and 6 positions.

Presence of fluorine atoms

Two on the phenyl ring
The addition of fluorine atoms can influence the compound's reactivity, stability, and solubility.

Potential applications

Pharmaceutical and agrochemical industries
The unique properties of 1H-Pyrrole, 2-(2,6-difluorophenyl)- may make it useful in the development of new drugs or agrochemicals.

Building block in organic synthesis

Possible use in creating various organic compounds
The compound could serve as a starting material or intermediate for the synthesis of other valuable organic molecules.

Further research needed

Specific uses and properties would depend on ongoing research and development in organic chemistry
The full potential of 1H-Pyrrole, 2-(2,6-difluorophenyl)- may not yet be known, and further study is required to understand its capabilities and limitations.

Upstream product

• 64248-56-2 1-bromo-2,6-difluorobenzene 
• 7697-45-2 sodium pyrrolide 
• 18063-02-0 2,6-difluorobenzoylchloride 

Downstream Products

• 1260226-92-3 tris((5-(2,6-difluorophenyl)-1H-pyrrol-2-yl)methyl)amine 

Relevant academic research and scientific papers

Slow magnetic relaxation in a family of trigonal pyramidal iron(II) pyrrolide complexes

We present a family of trigonal pyramidal iron(II) complexes supported by tris(pyrrolyl-α-methyl)amine ligands of the general formula [M(solv) n][(tpaR)Fe] (M = Na, R = tert-butyl (1), phenyl (4); M = K, R = mesityl (2), 2,4,6-triisopropylphenyl (3), 2,6-difluorophenyl (5)) and their characterization by X-ray crystallography, Moessbauer spectroscopy, and high-field EPR spectroscopy. Expanding on the discovery of slow magnetic relaxation in the recently reported mesityl derivative 2, this homologous series of high-spin iron(II) complexes enables an initial probe of how the ligand field influences the static and dynamic magnetic behavior. Magnetization experiments reveal large, uniaxial zero-field splitting parameters of D = -48, -44, -30, -26, and -6.2 cm-1 for 1-5, respectively, demonstrating that the strength of axial magnetic anisotropy scales with increasing ligand field strength at the iron(II) center. In the case of 2,6-difluorophenyl substituted 5, high-field EPR experiments provide an independent determination of the zero-field splitting parameter (D = -4.397(9) cm-1) that is in reasonable agreement with that obtained from fits to magnetization data. Ac magnetic susceptibility measurements indicate field-dependent, thermally activated spin reversal barriers in complexes 1, 2, and 4 of Ueff = 65, 42, and 25 cm-1, respectively, with the barrier of 1 constituting the highest relaxation barrier yet observed for a mononuclear transition metal complex. In addition, in the case of 1, the large range of temperatures in which slow relaxation is observed has enabled us to fit the entire Arrhenius curve simultaneously to three distinct relaxation processes. Finally, zero-field Moessbauer spectra collected for 1 and 4 also reveal the presence of slow magnetic relaxation, with two independent relaxation barriers in 4 corresponding to the barrier obtained from ac susceptibility data and to the 3D energy gap between the MS = ±2 and ±1 levels, respectively.

NEW METHODS FOR THE SYNTHESIS OF 2-ARYLPYRROLES

Two short and efficient synthetic approaches for -mostly unknown- 2-arylpyrroles are presented.The key intermediates 3 are conveniently obtained from commercially available acetophenones 5 (method I) or benzoic acid derivatives 10, 11 (method II).