115475-77-9

Upstream product

• 115475-76-8 2-(5-Acetoxy-3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-methoxy-5-methyl-benzoic acid methyl ester 
• 108-98-5 thiophenol 
• 115475-75-7 2-(3-Chloro-5-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-methoxy-5-methyl-benzoic acid methyl ester 

Downstream Products

• 115475-78-0 2-(5-Acetoxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-methoxy-5-methyl-benzoic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of The Gilvocarcin-M Aglycone

The synthesis of the aglycone of the antibiotic Gilvocarcin-M by a sequential Meerwein Diels-Alder route is reported.The D-ring of the aglycone is attached by a halogen atom directed Meerwein arylation reaction and the A-ring is attached by a halogen atom directed Diels-Alder reaction.In the key step the directing chlorine atom is removed by a new thiophenylation reduction sequence.