115475-75-7Relevant academic research and scientific papers
Synthesis of The Gilvocarcin-M Aglycone
McKenzie, Thomas C.,Hassen, Wesley,Macdonald, Simon J. F.
, p. 5435 - 5436 (1987)
The synthesis of the aglycone of the antibiotic Gilvocarcin-M by a sequential Meerwein Diels-Alder route is reported.The D-ring of the aglycone is attached by a halogen atom directed Meerwein arylation reaction and the A-ring is attached by a halogen atom directed Diels-Alder reaction.In the key step the directing chlorine atom is removed by a new thiophenylation reduction sequence.
