1154885-47-8

Upstream product

• 773837-37-9 sodium cyanide 
• 1215969-79-1 3-chloro-1-(3',4'-difluorophenyl)-propan-1-one 
• 367-11-3 ortho-difluorobenzene 

Downstream Products

• 1006614-50-1 (±)-trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 
• 1450897-33-2 4-(3,4-difluorophenyl)-4-hydroxybutanenitrile 
• 1006614-50-1 trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 
• 1450916-28-5 (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carbonitrile 
• 1450916-27-4 (S)-4-(3,4-difluorophenyl)-4-hydroxybutanenitrile 

Relevant academic research and scientific papers

SYNTHESIS OF 2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID

The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

Synthesis of 2-(3,4-difluorophenyl)cyclopropanecarboxylic acid

The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

5-(3-Phenyl-3-oxo-propyl)-1H-tetrazole derivatives

PCT No. PCT/EP98/04032 Sec. 371 Date Dec. 30, 1999 Sec. 102(e) Date Dec. 30, 1999 PCT Filed Jun. 25, 1998 PCT Pub. No. WO99/02506 PCT Pub. Date Jan. 21, 19995-(3-phenyl-3-oxo-propyl)-1H-tetrazole derivatives of formula (I) wherein each of R and R1, being